Nature

Award-winning microscopy image disqualified over AI use - Nature

A winning video showing beating airway cilia has been disqualified from the Small World in Motion competition for failing to comply with competition rules.Credit: Ning Xu/Nikon Small World The winni…

Hidden signals in sleep can predict future health - Nature

<li>Shah, A. S. et al.Am. J. Lifestyle Med. https://doi.org/10.1177/15598276251346752 (2025). Article Google Scholar </li><li>Ramos, A. R., Wheaton, A. G. &amp; Johnson, D. A. Prev. Chronic Dis.…

How to build a mouse: embryo development captured in stunning detail - Nature

By introducing and tracking mutations as the cells of a mouse embryo divide, researchers have mapped relationship between cells. Credit: Steve Gschmeissner/Science Photo Library Cell recorders based…

NASA releases trove of Moon data from historic Artemis II flight - Nature

Artemis II astronaut Jeremy Hansen captures images during the lunar flyby.Credit: NASA Planetary scientists have fresh Moon joy to explore. On 7 October, NASA released more than 800 gigabytes of ima…

A preinvasive regulatory T cell axis for lung cancer interception - Nature

An effector regulatory T cell circuit is identified that can be monitored in blood samples to track the development of lung cancer, and blockade of this immune network in the preinvasive setting&nbsp;can&nbsp;intercept tumorigenesis to reduce tumour incidence…

A split attractor design for rapidly writing a navigational goal - Nature

The&nbsp;recurrent h∆K–PFG neural circuit generates persistent heading memories through slow excitation, fast inhibition and a&nbsp;disinhibitory&nbsp;gate, where disinhibition controls the functional&nbsp;coupling of the network to&nbsp;rapidly transition be…

A thorium-229 optical nuclear clock with feedback loop - Nature

Laser set-up In the 229Th interrogation system, a commercial laser (FHG-TA Pro, TOPTICA) provides an output power of approximately 500mW at a wavelength of 296.8nm, frequency-quadrupled in two doubl…

tRNA dosage regulates lineage dependency and resistance in prostate cancer - Nature

Patient sample collection Metastatic tumour samples constituting the UW TMAs were collected from patients with metastatic castration-resistant prostate cancer at the UWFred Hutchinson Cancer Center …

Retrofitting language models to operate over bytes - Nature

Byteified model architecture details Our architecture follows the same overall structure as earlier LTLMs, including DTP, BLT and H-Net (Related work in Methods). It consists of the following compon…

Spatially deterministic nucleation of 2D semiconductors by etching flux - Nature

Etching-flux-mediated single-centred nucleation of two-dimensional semiconductors is used to deterministically&nbsp;localize a single nucleation event, expanding semiconductor deposition from controlling where materials grow to controlling where and how cryst…

OpenAI posts 700 maths preprints online: mathematicians are up in arms - Nature

More than 700 preprints in various fields of mathematics were posted simultaneously by OpenAI.Credit: Monty Rakusen/DigitalVision via Getty The research community is in uproar after OpenAI released …

Prehistoric global migration of vanishing gut microbes with humans - Nature

<li>Sommer, F. &amp; Bäckhed, F. The gut microbiota masters of host development and physiology. Nat. Rev. Microbiol.11, 227238 (2013). Article CAS PubMed Google Scholar </li><li>Sanders, J…

Can your brain grow new neurons? How researchers are solving a century-old puzzle - Nature

For a long time, it was a truism in science that the human brain is born with all of the neurons it will ever have. But truisms can crumble, and this one is looking shaky. The brain struggles to mak…

Flu season could kick off ‘incredibly’ early — what scientists are watching - Nature

A variant of the H1N1 influenza virus is dominating flu season in the Northern Hemisphere so far this year. Shown here are H1N1 influenza virus particles (yellow) releasing from an infected lung cell…

Bacteria regulate collective behaviour by mechanosensing cell–cell collisions - Nature

Density-dependent regulation of collective order through collision sensing and collision-induced reversals provides a navigational advantage to Pseudomonas aeruginosa during surface colonization and navigation through micromazes.

Discovery of a second-generation planet candidate accreting onto a white dwarf - Nature

Niobium has been detected in the atmosphere of a young white dwarf, probably originating from a second-generation planet candidate being evaporated by the white dwarf. The planet probably formed from material ejected during the white dwarf progenitor’s death …

How bacterial immune systems sense phage infection - Nature

Bacteria deploy diverse immune systems to counter phage infection, yet how these systems sense invasion remains incompletely understood. This Review categorizes phage-derived triggers and outlines emerging principles that govern immune recognition of phage in…

Synergy between Enterobacteriaceae and diet mediates competition between dominant Bacteroidales in the human gut - Nature

Multiomic experiments using defined and native gut communities reveal that complex dietary glycans mediate the dominance of Prevotellaceae in non-industrialized gut metagenomes through signalling-mediated cross-feeding with Enterobacteriaceae.

Carbene transfer from thianthrenium ylides for cyclopropanation - nature.com

<li>Green, S. P. et al. Thermal stability and explosive hazard assessment of diazo compounds and diazo transfer reagents. Org. Process Res. Dev.24, 6784 (2020). Article CAS PubMed Google Sch…

Butterfly wing patterns in flight create powerful illusory motion cues - Nature

Butterfly wing patterns and flight dynamics work in tandem to create powerful visual illusions that confuse predators, potentially representing one of the most successful visual defence strategies in moving animals.

Scalable decision-making for games of imperfect information - Nature

Ataraxos, an AI for the board wargame Stratego, establishes a design pattern for reinforcement learning and search that is effective under large amounts of hidden information, a longstanding desideratum of the field of strategic decision-making.

Population-scale immune multiome atlas reveals regulatory disease mechanisms - Nature

<li>Program in Medical and Population Genetics, Broad Institute of MIT and Harvard, Cambridge, MA, USA Masahiro Kanai, Juha Karjalainen, Georgia Panagiotaropoulou, Yuanxiang Zhang, Zhili Zheng, Mark…

Spatiotemporal clonal architecture of the newborn mouse forebrain - Nature

Clonal barcoding across the newborn mouse forebrain reveals developmental principles whereby glutamatergic neurons and astrocytes remain locally derived, whereas widely dispersed GABAergic (γ-aminobutyric acid-producing) lineages link neurons with oligodendro…

Dynamic protrusions mediate crawling motility in Asgard archaea - Nature

Anoxic live-cell imaging shows actin-dependent crawling motility and dynamic protrusions in Asgard archaea, providing insights into cellular innovations that may have contributed to eukaryotic evolution.

Prion-like transmission of human tau strains in the mouse brain - Nature

Mouse experiments show that Alzheimer’s disease&nbsp;and corticobasal degeneration tau filaments retain their distinct structures during templated seeding, supporting strain-specific tau propagation and disease modelling.

Evolution of terrestrial anatomy revealed by a derived stem tetrapod - Nature

New anatomical evidence reclassifies Westlothiana as an aquatic stem tetrapod, showing that terrestrial limb adaptations evolved mosaically in transitional amphibious environments before crown tetrapods emerged.

Sugar-rich foods exacerbate antibiotic-induced microbiome disruption - Nature

Patients In this cohort study of adult allo-HCT recipients at Memorial Sloan Kettering Cancer Center in New York between 2017 and 2022, eligible participants had been admitted for Allo-HCT. Three ti…

I turn up late to meetings to dodge small talk. Am I wrong? - Nature

Credit: Carlo Bollo/Alamy The case I hate small talk. People who know me would be surprised to hear that, because I come across as a chatty extrovert I even have my own science podcast but when it …

How did Earth get its water? Inside the extreme machine seeking answers - Nature

Geoscientists have been debating whether Earth (right) trapped water in its interior during its formation some 4.5 billion years ago.Credit: SPL/Alamy Albuquerque, New Mexico The Z machine at Sandi…

How to make a brain: new experiments challenge existing picture - Nature

How a team of AIs discovered a promising lung-cancer drug - nature.com

After examining the results of thousands of clinical trials, a swarm of AI agents suggested that a protein that dampens immune responses could be the target for a promising treatment for lung cancer.…

Evolution and heterogeneity of lethal metastatic bladder cancer subtypes - nature.com

A rapid autopsy programme provides valuable resources to enable detailed molecular and genetic analyses of the temporal evolution of aggressive histological subtypes and therapy resistance in metastatic bladder cancer.

Targeted genomic integration and rearrangement using prime assembly - Nature

Prime assembly enables RNA-guided integration of medium-to-large DNA sequences in human cells without requiring double-strand breaks or cell cycle progression, and supports exon recoding, transgene insertion and megabase-scale rearrangements.

Reimagining research papers as interactive and reliable AI agents - Nature

Paper2Agent converts research papers into interactive artificial intelligence agents by turning manuscripts, code and data into model context protocol-based tool-invoking systems that reproduce original results, answer new scientific queries and collaborate t…

Overmassive black holes and little red dots naturally form in simulations - Nature

Observations from the JWST reveal an unexpectedly abundant population of little red dots and overmassive black holes in the early Universe, which are confirmed by their formation in fully cosmological radiation-hydrodynamic simulations.

Developmental xenocortication using human-derived organoids in mice - Nature

Genetically encoded cortical depletion Emx1-cre (JAX, B6.129S2-Emx1tm1(cre)Krj/J), Esco2fl/fl (JAX, B6N.129S-Esco2tm1.1Ge/J) and C57BL SCID (JAX, B6.Cg-Prkdcscid/SzJ) mice were used to generate the …

Map of brain ‘microproteins’ could offer new clues to Alzheimer’s disease - nature.com

Mapping microproteins in the brain might help to understand, and treat, Alzheimers disease.Credit: Zephyr/SPL More than 1,000 previously overlooked microproteins have been found in samples of human …

These bizarre, much-coveted microbes are revealing the origins of complex life - nature.com

Over two days in June, Emily Aguilar-Pine drove 2,500 kilometres from Bozeman, Montana, to Austin, Texas, with one of microbiologys most coveted organisms in the back of her mothers SUV. Inside some …

‘Stomach bugs’ send protective immune cells rushing from gut to brain - nature.com

Some immune cells make the long journey from the gut to membranes surrounding the brain. Credit: Steve Gschmeissner/SPL/Alamy Immune cells that fight stomach bugs can migrate from the gut to the bra…

Underground hydrogen could spur a green-energy revolution — if companies can find it - Nature

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